This is an opportunity to join the Oncology Bioscience group in Cambridge as a laboratory based in vitro bioscientist.

This is an opportunity to join the Oncology Bioscience group in Cambridge as a laboratory based in vitro bioscientist. We are seeking a highly motivated and skilled Senior Research Scientist (SRS) ideally with scientific and technical knowledge in Ras cancer biology. Working within a multidiscipline team you will play a pivotal role in supporting progression of Oncology drug discovery projects through delivering robust and high-quality preclinical data. You should have a background in Oncology, a good knowledge of cellular signalling pathways in cancer and a strong passion for experimental work & delivering data from the laboratory.

About AstraZeneca

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies.

Site description

Welcome to our Chesterford Research Park, one of over 400 sites here at AstraZeneca, providing a collaborative environment where everyone feels comfortable and able to be themselves is at the core of AstraZeneca's priorities, it's important to us that you bring your full self to work every day. To help you maintain your best self, here's a sneak peek into some of the things this site provides for you…high quality office facilities accommodating teams from our Oncology, BioPharmaceuticals R&D Organisations. Restaurant and bar facilities within the park along with space for recreational walks and jogging paths. The park hosts a health and fitness centre and provides coach and shuttle bus services to Cambridge City centre, easily accessible via regular running public transport, you can also park at the site. You will be required to move to the DISC in Cambridge at somepoint during 2023.

Business area

In the Oncology Business Unit we relentlessly follow the science, challenging the status quo to deliver more effective treatments to patients in need. Our dedication means we purposefully push back the limits of knowledge to change the practice of medicine. To ensure no patient is left behind, no matter what stage of disease. Fast-paced, it takes agility and responsiveness to stay committed in our pursuit of excellence. We work with focus to seek the unanswered questions - innovating, challenging accepted norms, quick decision-making and taking smart risks.

What you'll do

• Deliver high quality in vitro data according to the study plan as agreed with the team leader or project supervisor

• Provide interpretation of experimental data, identifying innovative solutions to problems and putting forward plans for further experiments

• Communicate experimental data and key findings in a clear and concise manner to project teams

• Generate and maintain clear experimental records

• Maintain an awareness of current developments in the literature to support projects, bring forward new target ideas or new technologies / assay methods

• Actively drive personal development within Oncology Bioscience, independently seeing opportunities where relevant.

Essential for the role

• Degree and PhD in a biological science with relevant lab-based experience

• Evidence of strong technical and experimental ability to deliver data from the lab

• Expertise in mammalian cell tissue culture techniques including cell line maintenance, transfection, transduction, CRISPR gene editing and stable cell line generation

• Experienced in a range of in vitro cell based mechanistic techniques and assays including cellular proliferation and survival assays, flow cytometry and high-content imaging

• Expertise in a range of molecular biological techniques including molecular cloning, isolation and analysis of nucleic acids and proteins

• Strong communication and presentation skills

• Positive and team player with willingness to improve and learn new skills

• Passion for experimental work with a desire to pursue a career from the lab

• Good understanding of cancer cell biology

Desirable for the role

• Scientific and technical knowledge in Ras cancer biology

• Lab-based drug discovery experience in academic or pharmaceutical company setting

• An understanding of the drug discovery process

Why AstraZeneca?

At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. A culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We're on a journey to pioneer the future of healthcare.

So, what's next?

• Are you already considering joining the team? Good, because we can't wait to hear from you.

• Are you ready to bring ideas and fresh thinking to the table? Brilliant! We have one seat available, and we hope it's yours.

• If you're curious to know more; please contact Louise Bennett

Competitive salary package and benefits

Close Date: 21/04/2023

Where can I find out more?

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